This page helps you optimize the cost vs. error function of your high-throughput bulk competition experiments. Use the tools below to visualize some key results from Matuszewski et al. 2016 for values that are relevant to your proposed experiment(s). The publication in Genetics can be found here (or see the pre-print version here).
|Use the sliders to visualize the minimum error for different values of the sequencing depth per sampled time point (D), the number of mutants (K), and the total duration of the experiment (tτ). Use the red tabs to toggle between viewing the results for equally and unequally spaced sampling time points.|
|# Reads per Sample (D)||# Mutants (K)||Duration (tτ)|
|# Time Points (τ)||Spacing of Time Points|
|as fraction of duration|